Int J Mol Sci: BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome

BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome Petra Gorombei, Fabien Guidez, Saravanan Ganesan, Mathieu Chiquet, Andrea Pellagatti, Laure Goursaud, Nilgun Tekin, Stephanie Beurlet, Satyananda Patel, Laura Guerenne, Carole Le Pogam, Niclas Read more…

Am J Hematol: Cytogenetic and molecular abnormalities in Waldenström’s macroglobulinemia patients: correlations and prognostic impact

Cytogenetic and molecular abnormalities in Waldenström’s macroglobulinemia patients: correlations and prognostic impact Daphné Krzisch, Nayara Guedes, Clémentine Boccon-Gibod, Marine Baron, Clotilde Bravetti, Frédéric Davi, Marine Armand, Luce Smagghe, Jonathan Caron, Olivier A Bernard, Santos Susin, Elise Chapiro, Véronique Leblond, Florence Nguyen-Khac, Damien Roos-Weil, FILO (French Innovative Leukemia Organization) group Am Read more…

J Exp Med: Autoimmunity affecting the biliary tract fuels the immunosurveillance of cholangiocarcinoma

Autoimmunity affecting the biliary tract fuels the immunosurveillance of cholangiocarcinoma Juliette Paillet, Céleste Plantureux, Sarah Lévesque, Julie Le Naour, Gautier Stoll, Allan Sauvat, Pamela Caudana, Jimena Tosello Boari, Norma Bloy, Sylvie Lachkar, Isabelle Martins, Paule Opolon, Andrea Checcoli, Agathe Delaune, Noémie Robil, Pierre de la Grange, Juliette Hamroune, Franck Letourneur, Read more…

Mol Biol Rep: Genes coding for transcription factors involved in stem cell maintenance are repressed by TGF-β and downstream of Slug/Snail2 in COPD bronchial epithelial progenitors.

Genes coding for transcription factors involved in stem cell maintenance are repressed by TGF-β and downstream of Slug/Snail2 in COPD bronchial epithelial progenitors. Pierre de la Grange , Ariane Jolly , Charlotte Courageux , Chamseddine Ben Brahim , Pascale Leroy Mol Biol Rep. 2021 Aug 26 Pubmed

Mol Psychiatry: Wnt/β-catenin pathway and cell adhesion deregulation in CSDE1-related intellectual disability and autism spectrum disorders.

Wnt/β-catenin pathway and cell adhesion deregulation in CSDE1-related intellectual disability and autism spectrum disorders. E El Khouri, J Ghoumid, D Haye, F Giuliano, L Drevillon, A Briand-Suleau, P De La Grange, V Nau, T Gaillon, T Bienvenu, H Jacquemin-Sablon, M Goossens, S Amselem, I Giurgea Mol Psychiatry. 2021 Apr 19. Read more…

Mol Neurobiol: Activation of Macrophages by Lysophosphatidic Acid through the Lysophosphatidic Acid Receptor 1 as a Novel Mechanism in Multiple Sclerosis Pathogenesis.

Activation of Macrophages by Lysophosphatidic Acid through the Lysophosphatidic Acid Receptor 1 as a Novel Mechanism in Multiple Sclerosis Pathogenesis. Jennifer Fransson, Ana Isabel Gómez-Conde, Jesús Romero-Imbroda, Oscar Fernández, Laura Leyva, Fernando Rodríguez de Fonseca, Jerold Chun, Celine Louapre, Anne Baron Van-Evercooren, Violetta Zujovic, Guillermo Estivill-Torrús, Beatriz García-Díaz Mol Neurobiol Read more…

Front Immunol: Characterization of Blood Immune Cells in Patients With Decompensated Cirrhosis Including ACLF.

Characterization of Blood Immune Cells in Patients With Decompensated Cirrhosis Including ACLF. Emmanuel Weiss, Pierre de la Grange, Mylène Defaye, Juan José Lozano, Ferrán Aguilar, Pushpa Hegde, Ariane Jolly, Lucile Moga, Sukriti Sukriti, Banwari Agarwal, Haqeeqat Gurm, Marion Tanguy, Johanne Poisson, Joan Clària, Paer-Selim Abback, Axel Périanin, Gautam Mehta, Rajiv Read more…

Stem Cell Rev Rep: Proliferation Genes Repressed by TGF-β Are Downstream of Slug/Snail2 in Normal Bronchial Epithelial Progenitors and Are Deregulated in COPD.

Proliferation Genes Repressed by TGF-β Are Downstream of Slug/Snail2 in Normal Bronchial Epithelial Progenitors and Are Deregulated in COPD. Chamseddine Ben Brahim, Charlotte Courageux, Ariane Jolly, Bérengère Ouine, Aurélie Cartier, Pierre de la Grange, Leanne de Koning, Pascale Leroy. Stem Cell Rev Rep. 2021 Jan 26 Pubmed

Acta Neuropathol Commun: Frequent SLC35A2 brain mosaicism in mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE)

Frequent SLC35A2 brain mosaicism in mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE). Thomas Bonduelle, Till Hartlieb, Sara Baldassari, Nam Suk Sim, Se Hoon Kim, Hoon-Chul Kang, Katja Kobow, Roland Coras, Mathilde Chipaux, Georg Dorfmüller, Homa Adle-Biassette, Eleonora Aronica, Jeong Ho Lee, Ingmar Blumcke, Stéphanie Baulac. Acta Read more…