Targeting the TNF/IAP pathway synergizes with anti-CD3 immunotherapy in T-cell acute lymphoblastic leukemia. Andrea Ávila Ávila, Kanokporn Nuantang, Mariana L Oliveira, Sabine Druillennec, Benedetta Zaniboni, Etienne Lengliné, Vahid Asnafi, Jacques Ghysdael, Christine Tran Quang Blood. 2024 May 23 Pubmed
Archetypal Analysis of Kidney Allograft Biopsies Using Next-generation Sequencing Technology Esteban Cortes Garcia, Alessia Giarraputo, Maud Racapé, Valentin Goutaudier, Cindy Ursule-Dufait, Pierre de la Grange, Franck Letourneur, Marc Raynaud, Clément Couderau, Fariza Mezine, Jessie Dagobert, Oriol Bestard, Francesc Moreso, Jean Villard, Fabian Halleck, Magali Giral, Sophie Brouard, Richard Danger, Pierre-Antoine Read more…
Microsatellite instability at U2AF-binding polypyrimidic tract sites perturbs alternative splicing during colorectal cancer initiation Vincent Jonchère, Hugo Montémont, Enora Le Scanf, Aurélie Siret, Quentin Letourneur, Emmanuel Tubacher, Christophe Battail, Assane Fall, Karim Labreche, Victor Renault, Toky Ratovomanana, Olivier Buhard, Ariane Jolly, Philippe Le Rouzic, Cody Feys, Emmanuelle Despras, Habib Zouali, Read more…
Antibody Mediated Rejection and T-cell Mediated Rejection Molecular Signatures Using Next-Generation Sequencing in Kidney Transplant Biopsies. Cortes Garcia E, Giarraputo A, Racapé M, Goutaudier V, Ursule-Dufait C, de la Grange P, Adoux L, Raynaud M, Couderau C, Mezine F, Dagobert J, Bestard O, Moreso F, Villard J, Halleck F, Giral Read more…
Erythropoietin induces tumour progression and CD39 expression on immune cells in a preclinical model of triple-negative breast cancer. Stéphanie Bessoles, Andrada Chiron, Guillaume Sarrabayrouse, Pierre De La Grange, Amine M Abina, Salima Hacein-Bey-Abina Immunology. 2024 Jul 2 Pubmed
Splicing targeting drugs highlight intron retention as an actionable vulnerability in advanced prostate cancer Chiara Naro, Ambra Antonioni, Vanessa Medici, Cinzia Caggiano, Ariane Jolly, Pierre de la Grange, Pamela Bielli, Maria Paola Paronetto, Claudio Sette J Exp Clin Cancer Res. 2024 Feb 27 Pubmed
Differential expression of paralog RNA binding proteins establishes a dynamic splicing program required for normal cerebral cortex development Eleonora Cesari, Donatella Farini, Vanessa Medici, Ingrid Ehrmann, Marika Guerra, Erika Testa, Chiara Naro, Maria Concetta Geloso, Vittoria Pagliarini, Livia La Barbera, Marcello D’Amelio, Tiziana Orsini, Stefano Farioli Vecchioli, Luca Tamagnone, Philippe Read more…
A cell-type-specific alternative splicing regulator shapes synapse properties in a trans-synaptic manner. Lisa Traunmüller, Jan Schulz, Raul Ortiz, Huijuan Feng, Elisabetta Furlanis, Andrea M Gomez, Dietmar Schreiner, Josef Bischofberger, Chaolin Zhang, Peter Scheiffele Cell Rep. Mar 28 Pubmed
BCL2 Inhibition Reveals a Dendritic Cell-Specific Immune Checkpoint That Controls Tumor Immunosurveillance Liwei Zhao #, Peng Liu #, Misha Mao, Shuai Zhang, Camille Bigenwald, Charles-Antoine Dutertre, Christian H K Lehmann, Hui Pan, Nicolas Paulhan, Lukas Amon, Aitziber Buqué, Takahiro Yamazaki, Lorenzo Galluzzi, Benoit Kloeckner, Aymeric Silvin, Yuhong Pan, Hui Chen, Read more…
Loss of Dicer in newborn melanocytes leads to premature hair greying and changes in integrin expression. Juliette U Bertrand, Valérie Petit, Zackie Aktary, Pierre DE LA Grange, Nadav Elkoshi, Pierre Sohier, Véronique Delmas, Carmit Levy, Lionel Larue J Invest Dermatol. 2023 Sep 20 Pubmed